• Title of article

    A facile, microwave-assisted, palladium-catalyzed arylation of acetone

  • Author/Authors

    Chobanian، نويسنده , , Harry R. and Liu، نويسنده , , Ping and Chioda، نويسنده , , Marc D. and Guo، نويسنده , , Yan and Lin، نويسنده , , Linus S. Lin، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2007
  • Pages
    4
  • From page
    1213
  • To page
    1216
  • Abstract
    We report an expedient method for the heteroarylation of acetone under tin-free conditions. The coupling is performed using the commercially available enol silane of acetone (2-trimethylsilyloxypropene) and a corresponding aryl bromide, chloride or triflate under microwave-assisted conditions, with tris(dibenzylideneacetone)dipalladium (Pd2(dba)3) or palladium acetate (Pd(OAc)2) and 2-(2′,6′-dimethoxybiphenyl)dicyclohexylphosphine (S-Phos) as the catalyst system.
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2007
  • Journal title
    Tetrahedron Letters
  • Record number

    1854211