Title of article
A highly regio- and chemoselective addition of carbon nucleophiles to pyrimidinones. A new route to C4 elaborated Biginelli compounds
Author/Authors
Singh، نويسنده , , Kamaljit and Arora، نويسنده , , Divya and Singh، نويسنده , , Sukhdeep، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
4
From page
1349
To page
1352
Abstract
Ethyl 6-methyl-pyrimidine-2-one-5-carboxylates react with C-nucleophiles in a diversity oriented synthetic sequence to afford C4 substituted congeners of medicinally potent Biginelli dihydropyrimidinones, in a highly regioselective manner.
Keywords
lithiation , Carbon nucleophiles , Regioselective addition , Biginelli compounds
Journal title
Tetrahedron Letters
Serial Year
2007
Journal title
Tetrahedron Letters
Record number
1854262
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