Title of article
Readily available amino acid building blocks for the synthesis of phosphole-containing peptides
Author/Authors
van Zutphen، نويسنده , , Steven and Margarit، نويسنده , , Vicente J. and Mora، نويسنده , , Guilhem and Le Floch، نويسنده , , Pascal، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
3
From page
2857
To page
2859
Abstract
Nucleophilic substitution of a phospholide anion onto protected 3-iodoalanine leads to the formation of an amino acid with an appended phosphole in excellent yield. Manipulation of the protecting groups, leads to building blocks suitable for the synthesis of phosphole-containing polypeptides.
Keywords
Fmoc protected , Phosphorus , Catalysis , Amino acid , peptide synthesis , Phosphole
Journal title
Tetrahedron Letters
Serial Year
2007
Journal title
Tetrahedron Letters
Record number
1854763
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