Title of article
Cyclic disulfides as functional mimics of the histone deacetylase inhibitor FK-228
Author/Authors
Mays، نويسنده , , Jared R. and Restituyo، نويسنده , , José A. and Katzenberger، نويسنده , , Rebeccah J. and Wassarman، نويسنده , , David A. and Rajski، نويسنده , , Scott R.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
5
From page
4579
To page
4583
Abstract
FK-228 is a potent histone deacetylase (HDAC) inhibitor with tremendous therapeutic potential against a wide array of human cancers. We describe the development of analogs that share FK-228’s novel mechanism of activation and HDAC inhibition.
Journal title
Tetrahedron Letters
Serial Year
2007
Journal title
Tetrahedron Letters
Record number
1855373
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