Title of article
Total synthesis of aculeatins A and B via a tethered oxa-Michael approach
Author/Authors
Chandrasekhar، نويسنده , , S. and Rambabu، نويسنده , , Ch. and Shyamsunder، نويسنده , , T.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
3
From page
4683
To page
4685
Abstract
A stereocontrolled total synthesis of aculeatins A and B has been achieved in eight steps and in 15% overall yield. The key feature of this synthetic approach is the application of a Marouka allylation and tethered intramolecular oxa-Michael reaction to install the required stereocentres on the tetrahydropyran ring.
Keywords
Spirocyclic natural products , Aculeatin , Marouka allylation , Oxa-Michael reaction
Journal title
Tetrahedron Letters
Serial Year
2007
Journal title
Tetrahedron Letters
Record number
1855441
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