Title of article
Indium triflate catalyzed reaction of diisopropyl diazomethylphosphonate with imines as a new approach to cis- and trans-aziridine-2-phosphonates
Author/Authors
Pellicciari، نويسنده , , Roberto and Amori، نويسنده , , Laura and Kuznetsova، نويسنده , , Natalia and Zlotsky، نويسنده , , Simon and Gioiello، نويسنده , , Antimo، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
4
From page
4911
To page
4914
Abstract
A new and efficient synthesis of cis- and trans-aziridine-2-phosphonates by metal-catalyzed aziridination reaction of diisopropyl diazomethylphosphonate and substituted aryl imines is reported. By exploring the influence of different Lewis acids employed as catalysts, imine nitrogen substituents, and the solvent effects we conclude that the best results are obtained when N-diphenylmethyl-substituted benzylimines are reacted with diisopropyl diazomethylphosphonate in methylene chloride at 0 °C in the presence of In(OTf)3 as catalyst.
Keywords
Aziridines-2-phosphonates , Diisopropyl diazomethylphosphonate , imines , In(OTf)3
Journal title
Tetrahedron Letters
Serial Year
2007
Journal title
Tetrahedron Letters
Record number
1855550
Link To Document