Title of article
Regioselective acylation of 6-O-protected octyl β-d-glucopyranosides by DMAP catalysis
Author/Authors
Muramatsu، نويسنده , , Wataru and Kawabata، نويسنده , , Takeo، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
3
From page
5031
To page
5033
Abstract
Regioselectivity of acylation of 6-O-protected octyl β-d-glucopyranosides was investigated. Treatment of octyl 6-O-methyl-β-d-glucopyranoside with isobutyric anhydride in the presence of DMAP in toluene at −40 °C gave 3-O-isobutyryl derivative in >99% regioselectivity. Similar treatment of octyl 6-O-TBS-β-d-glucopyranoside at −20 °C also gave 3-O-isobutyryl derivative in >99% regioselectivity.
Keywords
acylation , regioselectivity , Glucopyranoside , DMAP
Journal title
Tetrahedron Letters
Serial Year
2007
Journal title
Tetrahedron Letters
Record number
1855611
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