Title of article
On the synthesis of β-bromohydrine ethers via intermolecular alkoxyl radical addition to bicyclo[2.2.1]heptene
Author/Authors
Hartung، نويسنده , , Jens and Schneiders، نويسنده , , Nina and Gottwald، نويسنده , , Thomas، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
4
From page
6027
To page
6030
Abstract
Primary, secondary, and tertiary alkoxyl radicals add exo-selectively to the olefinic π-bond in bicyclo[2.2.1]heptene to afford exo-2-alkoxybicyclo[2.2.1]hept-3-yl radicals, which are trapped with BrCCl3 preferentially from the endo face to furnish β-bromohydrine ethers in 23–67% yield.
Keywords
Alkoxyl radical , Homolytic bromination , stereoselective synthesis , Tertiary thiohydroxamic acid O-esters , Intermolecular addition
Journal title
Tetrahedron Letters
Serial Year
2007
Journal title
Tetrahedron Letters
Record number
1856141
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