Title of article
One-pot conversion of 1,1-dibromoalkenes into internal alkynes by sequential Suzuki–Miyaura and dehydrobromination reactions
Author/Authors
Giorgio Chelucci، نويسنده , , Giorgio and Capitta، نويسنده , , Francesca and Baldino، نويسنده , , Salvatore and Pinna، نويسنده , , Gerard A.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
4
From page
6514
To page
6517
Abstract
A protocol for the one-pot synthesis of internal alkynes from 1,1-dibromoalkenes is reported. The method is hinged upon the Suzuki–Miyaura cross-coupling of 2-aryl- or 2-heteroaryl-1,1-dibromoalkenes with aryl or heteroaryl boronic acids or borate esters followed by dehydrobromination of the intermediate coupled products. Yields up to 89% were obtained.
Keywords
Alkynes , alkenes , 1 , Suzuki–Miyaura reaction , Palladium catalysts , 1-Dibromoalkenes
Journal title
Tetrahedron Letters
Serial Year
2007
Journal title
Tetrahedron Letters
Record number
1856414
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