Title of article
Rapid synthesis of 2,3-disubstituted-quinazolin-4-ones enhanced by microwave-assisted decomposition of formamide
Author/Authors
Kostakis، نويسنده , , Ioannis K. and Elomri، نويسنده , , Abdelhakim and Seguin، نويسنده , , Elisabeth and Iannelli، نويسنده , , Mauro and Besson، نويسنده , , Thierry، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
5
From page
6609
To page
6613
Abstract
An efficient methodology for the preparation of a series of 2,3-disubstituted-quinazolin-4(3H)-ones is described via a three step reaction from anthranilic acid. The obtained results also reveal that microwave-assisted rapid decomposition of formamide under controlled conditions of power, temperature and time is a very convenient source of ammonia for the synthesis of 2-substituted-quinazolin-4(3H)-ones and other rings.
Keywords
microwave-assisted chemistry , quinazolin-4-ones , Benzoxazin-4-ones , formamide
Journal title
Tetrahedron Letters
Serial Year
2007
Journal title
Tetrahedron Letters
Record number
1856463
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