Title of article
Asymmetric oxidation of 1,2-diols using N-bromosuccinimide in the presence of chiral copper catalyst
Author/Authors
Onomura، نويسنده , , Osamu and Arimoto، نويسنده , , Hitomi and Matsumura، نويسنده , , Yoshihiro and Demizu، نويسنده , , Yosuke، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
5
From page
8668
To page
8672
Abstract
Asymmetric oxidation of 1,2-diols using N-bromosuccinimide (NBS) in the presence of copper(II) triflate and (R,R)-Ph-BOX has been exploited. This oxidation was applicable to asymmetric desymmetrization of meso-hydrobenzoin and kinetic resolution of dl-hydrobenzoin and racemic-cycloalkane-cis-1,2-diols to afford optically active α-ketoalcohols with good to high enantiomeric excess.
Keywords
asymmetric oxidation , ?-Ketoalcohol , vic-Diol , Copper complex
Journal title
Tetrahedron Letters
Serial Year
2007
Journal title
Tetrahedron Letters
Record number
1857457
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