• Title of article

    Facile reduction of malonate derivatives using NaBH4/Br2: an efficient route to 1,3-diols

  • Author/Authors

    Tudge، نويسنده , , Matthew and Mashima، نويسنده , , Hiroko and Savarin، نويسنده , , Cecile and Humphrey، نويسنده , , Guy and Davies، نويسنده , , Ian، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2008
  • Pages
    4
  • From page
    1041
  • To page
    1044
  • Abstract
    Borane–dimethoxyethane generated from sodium borohydride–bromine mixtures efficiently reduces a wide range of malonate derivatives to the corresponding 1,3-diols. This new reagent system represents a milder alternative to current methods available, providing the requisite 1,3-diols in higher yields over shorter reaction times.
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2008
  • Journal title
    Tetrahedron Letters
  • Record number

    1858154