Title of article
Organocatalytic enantioselective Friedel–Crafts alkylation of simple phenols with trifluoropyruvate
Author/Authors
Zhao، نويسنده , , Junling and Liu، نويسنده , , Li and Gu، نويسنده , , Chun-Ling and Wang، نويسنده , , Dong and Chen، نويسنده , , Yong-Jun، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
4
From page
1476
To page
1479
Abstract
Enantioselective Friedel–Crafts alkylation of simple phenols (4a–j) with 3,3,3-trifluoropyruvate (3) was accomplished by using chiral cinchona alkaloid catalyst 2h (10 mol %). High yields and enantioselectivities (71–94% ee) of the Friedel–Crafts alkylation products were obtained.
Keywords
phenol , trifluoropyruvate , organocatalysis , Enantioselective Friedel–Crafts alkylation
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1858360
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