Title of article
A highly efficient total synthesis of (R)-(+)-muscopyridine by intramolecular [4+2] cycloaddition of bisketene
Author/Authors
Suwa، نويسنده , , Kie and Morie، نويسنده , , Yasuko and Suzuki، نويسنده , , Yumiko and Ikeda، نويسنده , , Kiyoshi and Sato، نويسنده , , Masayuki، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
4
From page
1510
To page
1513
Abstract
A highly efficient total synthesis of (R)-(+)-muscopyridine 1 has been accomplished in 12 steps with 40% overall yield. A highlight of the synthesis is the intramolecular [4+2] cycloaddition of bisketene to afford a bridged pyrone and ring transformation of the pyrone to afford pyridine derivatives.
Keywords
intramolecular cycloaddition , Bisketene , ring transformation , Muscopyridine
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1858382
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