Title of article
Synthesis of a hemifluorinated amphiphile designed for self-assembly and two-dimensional crystallization of membrane protein
Author/Authors
Dauvergne، نويسنده , , Julien and Polidori، نويسنده , , Ange and Vénien-Bryan، نويسنده , , Catherine and Pucci، نويسنده , , Bernard، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
4
From page
2247
To page
2250
Abstract
The work reported herein deals with the synthesis and the preliminary physical–chemical analysis of new hemifluorinated surfactant made up of one fluorinated chain linked to a tricarboxylic acid polar head which is able to complex a Ni atom and should favor the two-dimensional crystallization of membrane proteins. Such a compound forms a Langmuir film which is a fluid at 20 °C and not perturbed by the presence of hydrocarbon detergent in aqueous solution.
Keywords
Hemifluorinated surfactants , membrane proteins , Langmuir film , Nickel complexation , 2D proteins crystallization
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1858761
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