Title of article
Chemo- and regioselective ethynylation of 4,5,6,7-tetrahydroindoles with ethyl 3-halo-2-propynoates
Author/Authors
Trofimov، نويسنده , , Boris A. and Sobenina، نويسنده , , Lyubov’ N. and Stepanova، نويسنده , , Zinaida V. and Petrova، نويسنده , , Ol’ga V. and Ushakov، نويسنده , , Igor’ A. and Mikhaleva، نويسنده , , Al’bina I.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
4
From page
3946
To page
3949
Abstract
4,5,6,7-Tetrahydroindoles undergo a rapid, facile (rt, 60 min) ethynylation with ethyl 3-halo-2-propynoates upon grinding with solid K2CO3 (without solvent) at C-2 of the tetrahydroindole ring to afford ethyl 3-(4,5,6,7-tetrahydroindol-2-yl)-2-propynoates in 62–90% yield.
Keywords
4 , Active surface , K2CO3 , cross-coupling , indoles , 6 , 5 , 7-Tetrahydroindoles
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1859542
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