Title of article
Radical–polar crossover domino reactions involving organozinc reagents and β-(allyloxy)-enoates
Author/Authors
Giboulot، نويسنده , , Steven and Pérez-Luna، نويسنده , , Alejandro and Botuha، نويسنده , , Candice and Ferreira، نويسنده , , Franck and Chemla، نويسنده , , Fabrice، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
4
From page
3963
To page
3966
Abstract
Organozinc reagents (organozinc halides, diorganozincs and mixed copper–zinc reagents) react with β-(allyloxy)-enoates via a radical–polar crossover process to afford substituted furans in one single synthetic step following a domino reaction involving Michael addition and carbocyclisation. Reversal of diastereoselectivity can be obtained varying the organometallic and/or the reaction conditions.
Keywords
domino reactions , Radical–polar crossover , radicals , organozinc reagents , Furans
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1859547
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