Title of article
Friedel–Crafts and modified Vorbrüggen ribosylation. A short synthesis of aryl and heteroaryl-C-nucleosides
Author/Authors
Spadafora، نويسنده , , Marie and Mehiri، نويسنده , , Mohamed and Burger، نويسنده , , Alain and Benhida، نويسنده , , Rachid، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
5
From page
3967
To page
3971
Abstract
A direct coupling of aryl donor and tetra-O-acetylribose in the presence of Lewis acid led to β-C-nucleosides in good yields. In contrast, for deactivated electron-poor aromatics, a modified Vorbrüggen ribosylation reaction was investigated and successfully applied in the case of 2-trimethylsilyl-thiazole.
Keywords
Modified Vorbrüggen reaction , Friedel–Crafts ribosylation , C-nucleosides
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1859548
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