Title of article
Oxidant-controlled regioselectivity in the oxidative arylation of N-acetylindoles
Author/Authors
Shathaverdhan Potavathri، نويسنده , , Shathaverdhan and Dumas، نويسنده , , Ashley S. and Dwight، نويسنده , , Timothy A. and Naumiec، نويسنده , , Gregory R. and Hammann، نويسنده , , Jeffrey M. and DeBoef، نويسنده , , Brenton، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
4
From page
4050
To page
4053
Abstract
N-Acetylindoles can be oxidatively coupled with arenes such as benzene or pentafluorobenzene in dioxane. The use of Cu(OAc)2 as the stoichiometric oxidant produces selective arylation at the 3-position of indole while AgOAc produces selective arylation at indole’s 2-position.
Keywords
regioselective , arylation , C–H functionalization , indole , oxidative coupling , PALLADIUM
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1859585
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