Title of article
A simple approach to highly functionalized benzo[b]furans from phenols and aryl iodides via aryl propargyl ethers
Author/Authors
Lingam، نويسنده , , V.S. Prasada Rao and Vinodkumar، نويسنده , , Ramanatham and Mukkanti، نويسنده , , Khagga and Thomas، نويسنده , , Abraham and Gopalan، نويسنده , , Balasubramanian، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
5
From page
4260
To page
4264
Abstract
A variety of mono- and disubstituted phenols are alkylated with propargyl bromide to give phenyl 2-propynyl ethers, which were further coupled with aryl iodides under Sonogashira reaction conditions to give 3-phenoxy-1-aryl-1-propyne derivatives. The latter compounds underwent an initial Claisen rearrangement followed by ring closure to give functionalized benzo[b]furans in moderate to good yields.
Keywords
Aryl propargyl ethers , Sonogashira coupling , Claisen rearrangement
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1859692
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