Title of article
Lipase-catalyzed preparation of corticosteroid 17α-esters endowed with antiandrogenic activity
Author/Authors
Ferraboschi، نويسنده , , Patrizia and Mieri، نويسنده , , Maria De and Ragonesi، نويسنده , , Laura، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
3
From page
4610
To page
4612
Abstract
Several 17α-monoesters of cortexolone and its Δ9-derivative are endowed with antiandrogenic activity. Their synthesis can be accomplished by means of a lipase-catalyzed chemoselective alcoholysis of the corresponding 17α,21-diesters.
Keywords
Lipase , corticosteroid , antiandrogen , Chemoselective alcoholysis
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1859872
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