Title of article
Greener and rapid access to bio-active heterocycles: one-pot solvent-free synthesis of 1,3,4-oxadiazoles and 1,3,4-thiadiazoles
Author/Authors
Polshettiwar، نويسنده , , Vivek and Varma، نويسنده , , Rajender S.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
5
From page
879
To page
883
Abstract
A novel one-pot solvent-free synthesis of 1,3,4-oxadiazoles and 1,3,4-thiadiazoles by condensation of acid hydrazide and triethyl orthoalkanates under microwave irradiations is reported. This green protocol was catalyzed efficiently by solid supported Nafion®NR50 and phosphorus pentasulfide in alumina (P4S10/Al2O3) with excellent yields.
Keywords
microwave irradiation , 1 , 3 , 1 , 3 , 4-oxadiazole , 4-thiadiazole , Nafion , solvent-free reaction , P4S10/Al2O3
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1860226
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