Title of article
Concomitant morpholine ring contraction and pyridine lithiation in 4-morpholinopyridine: straightforward access to N-pyridyl oxazolidines
Author/Authors
Gros، نويسنده , , Philippe C. and Doudouh، نويسنده , , Abdelhatif and Woltermann، نويسنده , , Christopher، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
3
From page
4717
To page
4719
Abstract
The reaction of 4-morpholinopyridine with TMSCH2Li induced an unprecedented anionic ring contraction of the morpholine ring in an exo-trig mode while lithiating the pyridine ring regioselectively at C-3. The one-pot process offers a straightforward route to functional oxazolidinyl pyridines.
Keywords
Morpholinopyridine , Oxazolidine , Ring contraction , lithiation
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1860437
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