Title of article
Mono-acylation of piperazine and homopiperazine via ionic immobilization
Author/Authors
Pringle، نويسنده , , Wallace، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
3
From page
5047
To page
5049
Abstract
A method for the selective mono-acylation of piperazine and homopiperazine has been developed. In a flow system, initially the diamine is ionically immobilized on a sulfonic acid funtionalized silica gel, acylated with an appropriate reagent and finally liberated with ammonic methanol. Examples with high yield and purity are presented.
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1860648
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