Title of article
The Morita–Baylis–Hillman reaction in aqueous–organic solvent system
Author/Authors
de Souza، نويسنده , , Rodrigo O.M.A. and Pereira، نويسنده , , Vera L.P. and Esteves، نويسنده , , Pierre M. and Vasconcellos، نويسنده , , Mario L.A. A.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
4
From page
5902
To page
5905
Abstract
We have found that water and organic solvents mixed at different proportions can give good to excellent yields and short reaction times for the Morita–Baylis–Hillman reaction. The present Letter details our findings in the Morita–Baylis–Hillman reaction between several aromatic aldehydes and methyl acrylate or acrylonitrile. The selection of the catalyst was also evaluated and DABCO affored the best results when compared to DBU, DMAP, HMT, Imidazole and Triethylamine.
Keywords
Morita–Baylis–Hillman reaction , Catalysis , Dabco , Water and biological active adducts
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1861082
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