Title of article
A stereo- and regio-controlled synthesis of bromothiophenyl C-nucleosides. Tandem bromination-ribosylation via halogen dance process
Author/Authors
Peyron، نويسنده , , Corinne and Navarre، نويسنده , , Jean Michel and Dubreuil، نويسنده , , Didier and Vierling، نويسنده , , Pierre and Benhida، نويسنده , , Rachid، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
4
From page
6171
To page
6174
Abstract
Metallation–ribosylation of 2-bromothiophene 1 when conducted at room temperature afforded the original glycosylated dibromothiophene 3b following a regiocontrolled halogen transfer-based halogen-dance process. Then, stereocontrolled reduction-cyclization of hemiacetals 3a–c allowed straightforward access to the halogenated thiophenyl-C-nucleosides 6a–c.
Keywords
halogen dance , C-nucleosides , Stereocontrolled synthesis , Tandem process
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1861265
Link To Document