Title of article
The search for a hair-growth stimulant: new radicicol analogues as WNT-5A expression inhibitors from Pochonia chlamydosporia var. chlamydosporia
Author/Authors
Shinonaga، نويسنده , , Hideki and Kawamura، نويسنده , , Yoji and Ikeda، نويسنده , , Akiko and Aoki، نويسنده , , Mari and Sakai، نويسنده , , Noriyoshi and Fujimoto، نويسنده , , Natsuko and Kawashima، نويسنده , , Akira، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2009
Pages
3
From page
108
To page
110
Abstract
WNT-5A, a secretory glycoprotein, is related to the proliferation of dermal papilla cells. While searching for an inhibitor of WNT-5A expression, we identified an active compound, radicicol (1), and isolated four unique analogues, pochonins G–J (2–5), from a culture broth of the fungus Pochonia chlamydosporia TF-0480. Structural elucidation of 2–5 and their biological activities against WNT-5A are described.
Journal title
Tetrahedron Letters
Serial Year
2009
Journal title
Tetrahedron Letters
Record number
1862185
Link To Document