Title of article
Examination of the olefin–olefin ring closing metathesis to prepare Latrunculin B
Author/Authors
She، نويسنده , , Jin and Lampe، نويسنده , , John W. and Polianski، نويسنده , , Alexandra B. and Watson، نويسنده , , Paul S.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2009
Pages
4
From page
298
To page
301
Abstract
Three subunits of the potent actin polymerization inhibitor Latrunculin B were synthesized and assembled using olefin–olefin ring closing metathesis chemistry to close the 14-membered macrocycle. Metathesis reactions of substrates with various remote protecting group patterns were examined and gave 6,7-E-lactones as the preferred products.
Journal title
Tetrahedron Letters
Serial Year
2009
Journal title
Tetrahedron Letters
Record number
1862310
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