• Title of article

    Design and development of arrayable syntheses to accelerate SAR studies of pyridopyrimidinone and pyrimidopyrimidinone

  • Author/Authors

    Wan ، نويسنده , , Zehong and Yan، نويسنده , , Hongxing and Hall، نويسنده , , Ralph F. and Lin، نويسنده , , Xichen and Livia، نويسنده , , Stefano and Respondek، نويسنده , , Tomasz and Widdowson، نويسنده , , Katherine L. and Zhu، نويسنده , , Chongjie and Callahan، نويسنده , , James F.، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2009
  • Pages
    3
  • From page
    370
  • To page
    372
  • Abstract
    Chemoselectivity of chlorine versus methylthio (–SCH3), methylsulfinyl (–SOCH3), or methylsulfonyl [–S(O)2CH3] in either functionalization or substitution of pyridopyrimidinone and pyrimidopyrimidinone was studied. Utilization to prepare final targets for accelerated SAR studies via two-dimensional array syntheses has been demonstrated in both systems.
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2009
  • Journal title
    Tetrahedron Letters
  • Record number

    1862354