Title of article
Improved Ritter reaction with CF3-containing oxirane for an access to central units of protease inhibitors
Author/Authors
Dos Santos، نويسنده , , Mickael and Crousse، نويسنده , , Benoit and Bonnet-Delpon، نويسنده , , Danièle، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2009
Pages
3
From page
857
To page
859
Abstract
The influence of fluorinated alcohols on the BF3·Et2O-promoted Ritter type reaction has been investigated. Trifluoroethanol/BF3·Et2O system allowed access to the central unit of protease inhibitors by the ring opening of fluorinated epoxide 2 with various nitriles.
Keywords
Ritter reaction , Protease inhibitors , epoxide , Fluorinated alcohols , fluorine
Journal title
Tetrahedron Letters
Serial Year
2009
Journal title
Tetrahedron Letters
Record number
1862675
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