• Title of article

    Practical cleavage of trifluoroacetamides with p-toluensulfonic acid

  • Author/Authors

    Spencer، نويسنده , , Cierra and Balsells، نويسنده , , Jaume and Li، نويسنده , , Hongmei، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2009
  • Pages
    3
  • From page
    1010
  • To page
    1012
  • Abstract
    A practical and efficient cleavage of trifluoroacetamides with p-TsOH·H2O has been developed. The deprotected amines are isolated directly from the reaction mixture as tosylate salts. This method can be applied to both secondary and tertiary trifluoroacetamides in good isolated yields.
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2009
  • Journal title
    Tetrahedron Letters
  • Record number

    1862767