Title of article
Indium/copper-mediated conjugate addition of unactivated alkyl iodides to α,β-unsaturated carbonyl compounds in water
Author/Authors
Shen، نويسنده , , Zhi-Liang and Cheong، نويسنده , , Hao-Lun and Loh، نويسنده , , Teck-Peng، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2009
Pages
4
From page
1051
To page
1054
Abstract
An efficient method for the conjugate addition of unactivated alkyl iodides to α,β-unsaturated carbonyl compounds using indium/copper in water is described. The reactions proceed more efficiently in water than in organic solvents. In, CuI, and InCl3 are all essential for efficient reaction. Formation of a symmetrical vic-diarylalkane is observed when an aryl-substituted alkene is used as substrate.
Keywords
Indium , Copper , conjugate addition , ?-unsaturated carbonyl compounds , water , ? , Alkyl iodide
Journal title
Tetrahedron Letters
Serial Year
2009
Journal title
Tetrahedron Letters
Record number
1862790
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