Title of article
Synthesis of 3,4-disubstituted 2(1H)-quinolinones via intramolecular Friedel–Crafts reaction of N-arylamides of Baylis–Hillman adducts
Author/Authors
Kim، نويسنده , , Ko Hoon and Lee، نويسنده , , Hyun Seung and Kim، نويسنده , , Jae Nyoung، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2009
Pages
3
From page
1249
To page
1251
Abstract
3,4-Disubstituted 2(1H)-quinolinones were synthesized starting from the Baylis–Hillman adducts via the following sequential processes: (i) hydrolysis of the Baylis–Hillman adduct to acid, (ii) EDC coupling with anilines, (iii) H2SO4-assisted intramolecular Friedel–Crafts cyclization, and the final (iv) DBU-mediated isomerization.
Keywords
N-Arylamides , Baylis–Hillman adducts , 2(1H)-Quinolinones , Friedel–Crafts reaction
Journal title
Tetrahedron Letters
Serial Year
2009
Journal title
Tetrahedron Letters
Record number
1862886
Link To Document