Title of article
Assymetric synthesis of (2S,3R)- and (2S,3S)-[2-13C;3-2H] glutamic acid
Author/Authors
Okuma، نويسنده , , Kosuke and Ono، نويسنده , , Akira M. and Tsuchiya، نويسنده , , Seiji and Oba، نويسنده , , Makoto and Nishiyama، نويسنده , , Kozaburo and Kainosho، نويسنده , , Masatsune and Terauchi، نويسنده , , Tsutomu، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2009
Pages
3
From page
1482
To page
1484
Abstract
We have developed a synthetic route for (2S,3R)- and (2S,3S)-[2-13C;3-2H] glutamic acids with high enantioselectivity. The key reactions in this synthesis are the asymmetric reduction of the 2,3-didehydroornithine derivative using the (S,S)-Et-DuPHOS-Rh catalyst and the oxidation of the δ-position by ruthenium catalysis.
Journal title
Tetrahedron Letters
Serial Year
2009
Journal title
Tetrahedron Letters
Record number
1863000
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