Title of article
A rare pyridine to pyrrole conversion leading to a side product in epoxide ring opening
Author/Authors
Pathirana، نويسنده , , Charles and Shukla، نويسنده , , Rajesh and Castoro، نويسنده , , John and Weaver، نويسنده , , Douglas and Byrne، نويسنده , , Liam and Pennarun-Thomas، نويسنده , , Gaelle and Palaniswamy، نويسنده , , Venkatapuram، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2009
Pages
2
From page
1586
To page
1587
Abstract
A minor side product in a manufacturing batch of the intermediate 4 was observed and separated. The minor side product 5 was purified by preparative HPLC and its structure was determined by the analysis of comprehensive NMR and MS data. The structure of 5 reveals that its mechanism of formation includes a rare conversion of a pyridine moiety to a pyrrole.
Keywords
pyridine , pyrrole , Ring contraction , Ring opening , Side product , epoxide
Journal title
Tetrahedron Letters
Serial Year
2009
Journal title
Tetrahedron Letters
Record number
1863059
Link To Document