Rhodium-catalyzed diastereoselective 1,2-addition of arylboronic acids to chiral trifluoroethyl imine

Rhodium-catalyzed 1,2-addition of arylboronic acids 4a–j to chiral trifluoroethyl imine 3 afforded diastereomerically enriched sulfinamides 5a–j. The chiral auxiliary of the sulfinamide products was readily removed under acidic methanolysis to provide the corresponding trifluoroethylamine analogs 6a–j.