Title of article
A one-pot procedure for trifluoroacetylation of arylamines using trifluoroacetic acid as a trifluoroacetylating reagent
Author/Authors
Ohtaka، نويسنده , , Junpei and Sakamoto، نويسنده , , Takeshi and Kikugawa، نويسنده , , Yasuo، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2009
Pages
3
From page
1681
To page
1683
Abstract
A convenient procedure for the preparation of aryl trifluoroacetamides from aryl amines is described that employs 2–4 M equiv of trifluoroacetic acid in refluxing xylene as a trifluoroacetylating agent. Addition of an amount of pyridine that is equimolar to the amount of trifluoroacetic acid present in the reaction mixture facilitates the trifluoroacetylation of rather basic arylamines.
Keywords
Trifluoroacetylation , trifluoroacetic acid , Arylamine , Xylene , pyridine
Journal title
Tetrahedron Letters
Serial Year
2009
Journal title
Tetrahedron Letters
Record number
1863109
Link To Document