Title of article
Synthesis of oxadiazole-2-oxide analogues as potential antischistosomal agents
Author/Authors
Rai، نويسنده , , Ganesha and Thomas، نويسنده , , Craig J. and Leister، نويسنده , , William F. Maloney، نويسنده , , David J.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2009
Pages
4
From page
1710
To page
1713
Abstract
The synthesis of several 1,2,5-oxadiazole-2-oxide (Furoxan) analogues is described herein. These compounds were prepared in an effort to probe the SAR around the phenyl substituent and oxadiazole core for our studies toward thioredoxin-glutathione reductase (TGR) inhibition and antischistosomal activity.
Journal title
Tetrahedron Letters
Serial Year
2009
Journal title
Tetrahedron Letters
Record number
1863131
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