Title of article
Synthesis of 2-aminocyclopropyl pyrrolidines from glycoaminonitriles
Author/Authors
Declerck، نويسنده , , Delphine and Josse، نويسنده , , Solen and Nhien، نويسنده , , Albert Nguyen Van and Postel، نويسنده , , Denis، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2009
Pages
3
From page
2171
To page
2173
Abstract
We have developed an expedient method for the synthesis of 2-aminocyclopropyl pyrrolidines from carbohydrate-derived α-aminonitriles involving up to five or six steps, the key step being the titanium-mediated aminocyclopropanation on the aminonitrile moiety, followed by cleavage of the protecting groups.
Keywords
Glycoaminonitriles , Cyclopropylamine , Titanium isopropoxide , pyrrolidine
Journal title
Tetrahedron Letters
Serial Year
2009
Journal title
Tetrahedron Letters
Record number
1863484
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