Title of article
Stereoselective synthesis of the cytotoxic macrolide aspergillide B
Author/Authors
Dيaz-Oltra، نويسنده , , Santiago and Angulo-Pachَn، نويسنده , , César A. and Kneeteman، نويسنده , , Marيa N. and Murga، نويسنده , , Juan and Carda-Broch، نويسنده , , Miguel and Marco-Castaٌo، نويسنده , , J. Alberto، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2009
Pages
3
From page
3783
To page
3785
Abstract
A total, stereoselective synthesis of the cytotoxic macrolide aspergillide B has been performed. A cross metathesis and a C-glycosidation via a Mukaiyama-type aldol reaction were key features of the synthesis. The macrocyclic lactone ring was created by means of the Yamaguchi procedure.
Keywords
Macrolides , Mukaiyama C-glycosidation , Aspergillides , Yamaguchi macrolactonization , Brown asymmetric allylation , Cross metathesis
Journal title
Tetrahedron Letters
Serial Year
2009
Journal title
Tetrahedron Letters
Record number
1864675
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