Title of article
Synthetic study of fomitellic acids: construction of the AB ring moiety
Author/Authors
Yamaoka، نويسنده , , Makoto and Fukatsu، نويسنده , , Yuichi and Nakazaki، نويسنده , , Atsuo and Kobayashi، نويسنده , , Susumu، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2009
Pages
4
From page
3849
To page
3852
Abstract
Stereocontrolled synthesis of a fully functionalized AB ring moiety of fomitellic acids was accomplished. The tricyclic skeleton was stereoselectively constructed by means of titanium(III)-mediated radical cascade cyclization of epoxypolyene. The stereochemistry at C1 and C3 was controlled by a vinylogous Mukaiyama aldol reaction and a Sharpless asymmetric epoxidation, respectively.
Keywords
Titanium(III)-mediated radical cascade cyclization , vinylogous Mukaiyama aldol reaction , Triterpenoid , Epoxypolyene
Journal title
Tetrahedron Letters
Serial Year
2009
Journal title
Tetrahedron Letters
Record number
1864723
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