Title of article
One-step construction of 2-substituted-4,6-diazaindoles from carboxylic acid derivatives
Author/Authors
Song، نويسنده , , Jinhua J. and Tan، نويسنده , , Zhulin and Reeves، نويسنده , , Jonathan T. and Fandrick، نويسنده , , Daniel R. and Lee، نويسنده , , Heewon and Yee، نويسنده , , Nathan K. and Senanayake، نويسنده , , Chris H.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2009
Pages
3
From page
3952
To page
3954
Abstract
Treatment of unprotected 5-amino-4-methylpyrimidine (2) with n-BuLi gave dianion 3. Direct condensation of the dianion with various carboxylic acid derivatives furnished a range of 2-substituted-4,6-diazaindoles in good yields in one step without the need for protecting groups or oxidation-state adjustment.
Journal title
Tetrahedron Letters
Serial Year
2009
Journal title
Tetrahedron Letters
Record number
1864808
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