• Title of article

    Friedel–Crafts-type alkylation in aqueous media using resin-supported peptide catalyst having polyleucine

  • Author/Authors

    Akagawa، نويسنده , , Kengo and Yamashita، نويسنده , , Takuhiro and Sakamoto، نويسنده , , Seiji and Kudo، نويسنده , , Kazuaki، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2009
  • Pages
    3
  • From page
    5602
  • To page
    5604
  • Abstract
    The asymmetric Friedel–Crafts-type alkylation in aqueous media was realized by the resin-supported N-terminal prolyl peptide catalyst having a polyleucine tether. The hydrophobic polyleucine chain in the peptide catalyst was essential for the reaction efficiency and enantioselectivity. The resin-bound peptide catalyst could be reused at least for five times.
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2009
  • Journal title
    Tetrahedron Letters
  • Record number

    1866002