Title of article
Xanthone in synthesis: a reactivity profile via directed lithiation of its dimethyl ketal
Author/Authors
Odrowaz-Sypniewski، نويسنده , , Michal R. and Tsoungas، نويسنده , , Petros G. and Varvounis، نويسنده , , George and Cordopatis، نويسنده , , Paul، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2009
Pages
3
From page
5981
To page
5983
Abstract
Xanthone, as its dimethyl ketal, undergoes functionalization with a synthetically useful degree of regioselectivity using a lithiation protocol. The core structure is regenerated during the work-up. Monosubstitution at C-4 or C-1 and disubstitution at C-4 and C-5 or C-1 and C-5 are observed. The substitution pattern appears to be dependent upon the experimental conditions.
Keywords
Xanthone , lithiation , Dimethyl ketal , Methylation
Journal title
Tetrahedron Letters
Serial Year
2009
Journal title
Tetrahedron Letters
Record number
1866269
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