Title of article
Regioselectivity in 2-X-pyrazine aminations by O-mesitylenesulfonylhydroxylamine
Author/Authors
Borodkin، نويسنده , , Gennady I. and Vorob’ev، نويسنده , , Aleksey Yu. and Shakirov، نويسنده , , Makhmut M. and Shubin، نويسنده , , Vyacheslav G.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2009
Pages
4
From page
6779
To page
6782
Abstract
The regioselectivity of 2-X-pyrazine aminations by O-mesitylenesulfonylhydroxylamine was studied experimentally and the results are discussed from the viewpoint of electronic and steric factors. DFT calculations are consistent with the reaction proceeding according to an SN2 mechanism.
Keywords
N-Amine salts , linear free energy relationship , Mechanism , Selectivity , DFT calculations , amination , azines
Journal title
Tetrahedron Letters
Serial Year
2009
Journal title
Tetrahedron Letters
Record number
1866848
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