Title of article
Tandem reversible addition–intramolecular lactonization for the synthesis of 3-functionalized phthalides
Author/Authors
Morakot Sakulsombat، نويسنده , , Morakot and Angelin، نويسنده , , Marcus and Ramstrِm، نويسنده , , Olof، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
4
From page
75
To page
78
Abstract
A new tandem process based on reversible nucleophilic addition and intramolecular lactonization of methyl 2-formylbenzoate leads to the efficient synthesis of 3-functionalized phthalides, which are important precursors for the synthesis of quinone skeletons via Hauser–Kraus annulation. The reactions are successfully carried out under mild conditions in single operations.
Journal title
Tetrahedron Letters
Serial Year
2010
Journal title
Tetrahedron Letters
Record number
1870470
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