• Title of article

    Negishi coupling of 2-pyridylzinc bromide—paradigm shift in cross-coupling chemistry?

  • Author/Authors

    Coleridge، نويسنده , , Brian M. and Bello، نويسنده , , Charles S. and Ellenberger، نويسنده , , David H. and Leitner، نويسنده , , Andreas، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2010
  • Pages
    3
  • From page
    357
  • To page
    359
  • Abstract
    The efficient cross-coupling of 2-pyridylzinc bromide with functionalized aryl halides has been accomplished by a simple and highly efficient protocol. To the best of our knowledge, we report the first shelf life study of 2-pyridylzinc bromide which confirms the excellent stability of this compound and underlines the synthetic value of organozinc reagents in the cross-coupling reactions of sensitive heterocyclic nucleophiles on academic and commercial scale.
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2010
  • Journal title
    Tetrahedron Letters
  • Record number

    1870667