Title of article
Trifluoroacetylation of amines with trifluoroacetic acid in the presence of trichloroacetonitrile and triphenylphosphine
Author/Authors
Kim، نويسنده , , Joong-Gon and Jang، نويسنده , , Doo Ok، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
3
From page
683
To page
685
Abstract
We developed a mild and convenient trifluoroacetylation process for amines using a combination of trichloroacetonitrile and triphenylphosphine. The reaction that we designed is applicable to the trifluoroacetylation of a wide variety of amines, including amines with stereogenic centers, which underwent trifluoroacetylation without racemization.
Keywords
Trifluoroacetlyation , Aminoalcohol , trifluoroacetic acid , Trichloroacetonitrile , Triphenylphosphine , Amine
Journal title
Tetrahedron Letters
Serial Year
2010
Journal title
Tetrahedron Letters
Record number
1870896
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