Title of article
A novel aza-Prins-Friedel–Crafts reaction for the synthesis of 4-arylpiperidines
Author/Authors
Yadav، نويسنده , , J.S and Subba Reddy، نويسنده , , B.V. and Ramesh، نويسنده , , K. and Narayana Kumar، نويسنده , , G.G.K.S. and Grée، نويسنده , , René، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
4
From page
818
To page
821
Abstract
Aldehyde, homoallylic amine and arene undergo smooth cyclization in the presence of BF3·OEt2 to afford 4-arylpiperidines in good yields and with high trans-selectivity. This is the first report on the preparation of 4-arylpiperidines via aza-Prins-Friedel–Crafts reaction.
Keywords
Aza-Prins-Friedel–Crafts reaction , Homoallylic Amines , 4-Arylpiperidines , arenes
Journal title
Tetrahedron Letters
Serial Year
2010
Journal title
Tetrahedron Letters
Record number
1870985
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