Title of article
1,4-syn-Asymmetric induction in the titanium-mediated aldol reactions of chiral methyl α-silyloxy ketones
Author/Authors
Lorente، نويسنده , , Adriana and Pellicena، نويسنده , , Miquel and Romea، نويسنده , , Pedro and Urpي، نويسنده , , Fèlix، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
4
From page
942
To page
945
Abstract
Good levels of 1,4-syn asymmetric induction are obtained in the TiCl4-mediated aldol reaction of methyl α-silyloxy ketones with achiral aldehydes. Such methodology represents a new approach to the substrate-controlled acetate aldol reaction, which can be useful to design more efficient syntheses of natural products.
Keywords
chiral ketones , titanium enolates , Stereoselective reactions , Acetate aldol reactions
Journal title
Tetrahedron Letters
Serial Year
2010
Journal title
Tetrahedron Letters
Record number
1871068
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